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16 April 2021

Hasan Kertmen

Pediatrics Specialist

Sixth Disease (Roseola Infantilis)

Sixth Disease (Roseola Infantilis)

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  • What is the sixth disease?
  • It is a viral disease caused by the herpes virus group (Human herpes virus 6, HHV 6). Roseola infantilis takes its nickname of the sixth disease from the list of six common childhood diseases.


  • Who gets it?
  • Sixth disease affects children aged 6 months to 3 years. It is more common especially between 6-18 months. Immune factors transmitted from the mother in babies younger than 6 months protect the babies from the disease. This incidence decreases after 4 years of age.
  • What are the symptoms?
  • Sixth disease is the cause of 20% of admissions to the emergency department due to fever. It starts with a cold and progresses with a high fever for 3-5 days. Fever can trigger seizures and may be> 40 ° C. Then the fever ends suddenly and followingly small, pink, flat or slightly raised rashes appear. The rash first begins to appear on the chest and back, then can spread to the face and arms. The rash starts 12 to 24 hours after the fever has passed and lasts 1-3 days. When the rash occurs, the child begins to feel better.


  • How is it treated?
  • It is only important to keep the fever under control in treatment. Febrile seizures are rarely reported. Abundant fluid consumption is beneficial in controlling fever. Sixth disease should be among the preliminary diagnoses in patients who come to the emergency service or outpatient clinic with high fever. Rashes that may occur during or after fever should be evaluated by a physician and differentiated from other important diseases that may occur.



Spec. Dr. Hasan KERTMEN

Pediatry Department